TY - JOUR T1 - Plant-based diets, pescatarian diets and COVID-19 severity: a population-based case–control study in six countries JF - BMJ Nutrition, Prevention & Health JO - BMJ Nutrition DO - 10.1136/bmjnph-2021-000272 SP - bmjnph-2021-000272 AU - Hyunju Kim AU - Casey M Rebholz AU - Sheila Hegde AU - Christine LaFiura AU - Madhunika Raghavan AU - John F Lloyd AU - Susan Cheng AU - Sara B Seidelmann Y1 - 2021/05/18 UR - http://nutrition.bmj.com/content/early/2021/05/18/bmjnph-2021-000272.abstract N2 - Background Several studies have hypothesised that dietary habits may play an important role in COVID-19 infection, severity of symptoms, and duration of illness. However, no previous studies have investigated the association between dietary patterns and COVID-19.Methods Healthcare workers (HCWs) from six countries (France, Germany, Italy, Spain, UK, USA) with substantial exposure to COVID-19 patients completed a web-based survey from 17 July to 25 September 2020. Participants provided information on demographic characteristics, dietary information, and COVID-19 outcomes. We used multivariable logistic regression models to evaluate the association between self-reported diets and COVID-19 infection, severity, and duration.Results There were 568 COVID-19 cases and 2316 controls. Among the 568 cases, 138 individuals had moderate-to-severe COVID-19 severity whereas 430 individuals had very mild to mild COVID-19 severity. After adjusting for important confounders, participants who reported following ‘plant-based diets’ and ‘plant-based diets or pescatarian diets’ had 73% (OR 0.27, 95% CI 0.10 to 0.81) and 59% (OR 0.41, 95% CI 0.17 to 0.99) lower odds of moderate-to-severe COVID-19 severity, respectively, compared with participants who did not follow these diets. Compared with participants who reported following ‘plant-based diets’, those who reported following ‘low carbohydrate, high protein diets’ had greater odds of moderate-to-severe COVID-19 (OR 3.86, 95% CI 1.13 to 13.24). No association was observed between self-reported diets and COVID-19 infection or duration.Conclusion In six countries, plant-based diets or pescatarian diets were associated with lower odds of moderate-to-severe COVID-19. These dietary patterns may be considered for protection against severe COVID-19.Data are not publicly available. ER -