RT Journal Article
SR Electronic
T1 Consumption of industrial processed foods and risk of premenopausal breast cancer among Latin American women: the PRECAMA study
JF BMJ Nutrition, Prevention & Health
JO BMJ Nutrition
FD BMJ Publishing Group Ltd
SP 1
OP 9
DO 10.1136/bmjnph-2021-000335
VO 5
IS 1
A1 Isabelle Romieu
A1 Neha Khandpur
A1 Aikaterini Katsikari
A1 Carine Biessy
A1 Gabriela Torres-Mejía
A1 Angélica Ángeles-Llerenas
A1 Isabel Alvarado-Cabrero
A1 Gloria Inés Sánchez
A1 Maria Elena Maldonado
A1 Carolina Porras
A1 Ana Cecilia Rodriguez
A1 Maria Luisa Garmendia
A1 Vèronique Chajés
A1 Elom K Aglago
A1 Peggy L Porter
A1 MingGang Lin
A1 Mathilde His
A1 Marc J Gunter
A1 Inge Huybrechts
A1 Sabina Rinaldi
A1 ,
YR 2022
UL http://nutrition.bmj.com/content/5/1/1.abstract
AB Ultra-processed food intake has been linked to an increased risk of breast cancer in Western populations. No data are available in the Latin American population although the consumption of ultra-processed foods is increasing rapidly in this region.We evaluated the association of ultra-processed food intake to breast cancer risk in a case–control study including 525 cases (women aged 20–45 years) and 525 matched population-based controls from Chile, Colombia, Costa Rica and Mexico. The degree of processing of foods was classified according to the NOVA classification.Overall, the major contributors to ultra-processed food intake were ready-to-eat/heat foods (18.2%), cakes and desserts (16.7%), carbonated and industrial fruit juice beverages (16.7%), breakfast cereals (12.9%), sausages and reconstituted meat products (12.1%), industrial bread (6.1%), dairy products and derivatives (7.6%) and package savoury snacks (6.1%). Ultra-processed food intake was positively associated with the risk of breast cancer in adjusted models (OR T3-T1=1.93; 95% CI=1.11 to 3.35). Specifically, a higher risk was observed with oestrogen receptor positive breast cancer (ORT3-T1=2.44, (95% CI=1.01 to 5.90, P-trend=0.049), while no significant association was observed with oestrogen receptor negative breast cancer (ORT3-T1=1.87, 95% CI=0.43 to 8.13, P-trend=0.36).Our findings suggest that the consumption of ultra-processed foods might increase the risk of breast cancer in young women in Latin America. Further studies should confirm these findings and disentangle specific mechanisms relating ultra-processed food intake and carcinogenic processes in the breast.Data are available upon reasonable request. PRECAMA data and biospecimens are available for investigators who seek to answer important questions on health and disease in the context of research projects that are consistent with the legal and ethical standard practices of IARC/WHO and the PRECAMA Centres. The primary responsibility for accessing the data belongs to the PRECAMA centres that provided them. The use of anonymised data from the PRECAMA study can be requested by contacting the corresponding author. The request will then be passed to members of the PRECAMA Steering Committee for deliberation.