RT Journal Article SR Electronic T1 Treatment of overweight and obesity in general practice: a cluster randomised trial JF BMJ Nutrition, Prevention & Health JO BMJ Nutrition FD BMJ Publishing Group Ltd SP e000721 DO 10.1136/bmjnph-2023-000721 A1 Nilsen, Morten Dag A1 Mdala, Ibrahimu A1 Werner, Erik L YR 2023 UL http://nutrition.bmj.com/content/early/2023/11/28/bmjnph-2023-000721.abstract AB Overweight and obesity are among the most serious health problems of our time.A majority of patients with overweight and obesity will first get in touch with health services through primary care. This makes it crucial to develop strategies to enable physicians in primary care to help and treat patients with overweight and obesity. The physicians tend to avoid this subject. The main reason is reported to be lack of knowledge and education, and that they have nothing concrete to offer their patients.We wanted to examine if a simple method with specific measures could be used in Norwegian general practice and achieve meaningful weight loss.23 physicians and 210 patients participated in the study.The physicians who participated were cluster randomised into either control group or intervention group. The physicians in the control group were told to follow their usual approach, while the physicians in the intervention group followed a fixed plan with specific diets given orally and in writing to the patients. The inclusion criteria for both groups were: body mass index (BMI)>30 kg/m2, or BMI>25 kg/m2 with at least one weight-related condition. Weight was measured at the start, then after 1 year and finally after 2 years in both groups.We found no significant weight loss in the control group. In the intervention group, there was a weight loss of at least 10% by 25.5% after the first year and 24.2% after the entire observation period. 53.5% of the patients lost at least 5% of their weight in the first year and nearly 45% after the entire observation period. We conclude that a simple tool with a specific diet and activity plan is feasible in general practice and may produce significant weight loss. Trial registration number: NCT03000062.Data are available in a public, open access repository.