Characteristics of primary sample and top and bottom quintile of 91-SNP Genetic Risk Score
| 91-SNP Genetic Risk Score | Total sample | ||
| Quintile 1 (lowest risk of obesity) | Quintile 5 (highest risk of obesity) | ||
| Total number of participants | 64 269 | 69 577 | 335 046 |
| BMI (kg/m2), mean (SD) | 26.5 (4.3) | 28.3 (5.1) | 27.4 (4.7) |
| Distance to nearest fast-food outlet (m), median (IQR) | 1172 (634–2302) | 1169 (626–2290) | 1171 (630–2301) |
| Number of PA facilities within 1 km of home address, median (IQR) | 1 (0–3) | 1 (0–3) | 1 (0–3) |
| Age (y), mean (SD) | 56.5 (8.0) | 56.5 (8.0) | 56.5 (8.0) |
| Sex (female), n (%) | 33 876 (52.7) | 35 923 (51.6) | 17 4872 (52.2) |
| Income (£), n (%) | |||
| Less than 18 000 | 14 154 (22.0) | 15 734 (22.6) | 74 556 (22.3) |
| 18 000–30 999 | 16 497 (25.7) | 18 270 (26.3) | 86 917 (25.9) |
| 31 000–51 999 | 17 013 (26.5) | 18 374 (26.4) | 88 721 (26.5) |
| 52 000–100 000 | 13 269 (20.7) | 13 738 (19.8) | 67 908 (20.3) |
| Greater than 100 000 | 3336 (5.2) | 3461 (5.0) | 16 944 (5.1) |
| Education, n (%) | |||
| College or university degree | 21 462 (33.4) | 22 412 (32.2) | 110 153 (32.9) |
| A levels/AS levels or equivalent | 7635 (11.9) | 7961 (11.4) | 39 017 (11.7) |
| O levels/GCSEs or equivalent | 14 262 (22.2) | 15 779 (22.7) | 74 966 (22.4) |
| CSEs or equivalent | 3500 (5.5) | 3933 (5.7) | 18 722 (5.6) |
| NVQ or HND or HNC or equivalent | 4266 (6.6) | 4782 (6.9) | 22 892 (6.8) |
| Other professional qualifications | 3302 (5.1) | 3527 (5.1) | 16 954 (5.1) |
| None of the above | 9842 (15.3) | 11 183 (16.1) | 52 342 (15.6) |
| Employment status, n (%) | |||
| Paid employment or self-employed | 38 217 (59.5) | 41 326 (59.4) | 199 280 (59.5) |
| Retired | 21 330 (33.2) | 23 096 (33.2) | 111 113 (33.2) |
| Unable to work | 1756 (2.7) | 2055 (3.0) | 9457 (2.8) |
| Unemployed | 769 (1.2) | 878 (1.3) | 4238 (1.3) |
| Home duties/carer/student/other | 2197 (3.4) | 2222 (3.2) | 10 958 (3.3) |
| Urbanicity (% urban dwelling) | 54 560 (84.9) | 59 018 (84.8) | 284 471 (84.9) |
| Area deprivation,* mean (SD) | −1.6 (2.9) | −1.6 (2.9) | −1.6 (2.9) |
| Residential density,† median (IQR) | 1794 (1041–2934) | 1801 (1043–2911) | 1798 (1044–2918) |
*2001 Townsend index score.
†Residential address points per 1 km street network buffer around home address.
AS, Advanced Study; BMI, body mass index; CSE, Certificate of Secondary Education; GCSE, General Certificate of Secondary Education; HNC, Higher National Certificate; HND, Higher National Diploma; NVQ, National Vocational Qualification; PA, physical activity; SNP, single-nucleotide polymorphism.