Table 3B

The genotype and allele associations with overweight/obesity

SNP (gene)Genotype/alleleORunadjusted (95% CI)P valueORadjusted (95% CI)P value
rs1205 (CRP)Genotype
CC11
CT0.48 (0.24 to 0.95)0.036*0.51 (0.24 to 1.07)0.156
TT0.88 (0.33 to 0.44)0.7890.96 (0.32 to 2.85)1.000
Allele
C11
T0.80 (0.51 to 1.26)0.3270.83 (0.51 to 1.37)0.488
rs5186 (AGTR1)Genotype
AA11
AC0.45 (0.23 to 0.89)0.021*0.34 (0.15 to 0.72)0.010*
CC4.99 (0.56 to 44.44)0.1494.59 (0.41 to 51.35)0.430
Allele
A11
C0.79 (0.47 to 1.35)0.3930.64 (0.36 to 1.14)0.134
rs234706 (CBS)Genotype
AA11
AG0.14 (0.05 to 0.41)0.000*0.21 (0.06 to 0.66)0.016*
GG0.56 (0.16 to 1.96)0.3641.31 (0.32 to 5.39)1.000
Allele
A11
G0.95 (0.61 to 1.47)0.8031.20 (0.74 to 1.94)0.454
rs602662 (FUT2)Genotype
AA11
AG0.69 (0.28 to 1.68)0.4150.73 (0.28 to 1.89)1.000
GG0.23 (0.09 to 0.58)0.002*0.26 (0.09 to 0.71)0.018*
Allele
A11
G0.93 (0.53 to 1.63)0.7960.45 (0.27 to 0.74)0.002*
rs1799889 (PAI-1)Genotype
AA11
AG0.42 (0.19 to 0.91)0.028*0.44 (0.19 to 1.01)0.112
GG0.26 (0.10 to 0.69)0.006*0.23 (0.08 to 0.66)0.012*
Allele
A11
G0.54 (0.34 to 0.84)0.006*0.51 (0.31 to 0.83)0.007*
rs1800871 (IL-10)Genotype
AA11
AG0.34 (0.14 to 0.86)0.022*0.34 (0.12 to 0.94)0.076
GG0.67 (0.27 to 1.66)0.3840.66 (0.24 to 1.85)0.876
Allele
A11
G0.95 (0.60 to 1.50)0.8260.95 (0.58 to 1.57)0.860
rs1801131 (MTHFR)Genotype
GG11
GT0.27 (0.09 to 0.75)0.012*0.26 (0.08 to 0.79)0.034*
TT0.52 (0.19 to 1.41)0.2000.50 (0.17 to 1.45)0.408
Allele
G11
T0.93 (0.58 to 1.47)0.7410.91 (0.55 to 1.49)0.715
rs1801133 (MTHFR)Genotype
AA11
AG0.29 (0.09 to 0.98)0.047*0.29 (0.08 to 1.10)0.070
GG0.51 (0.16 to 1.63)0.2550.66 (0.18 to 2.36)0.533
Allele
A11
G1.02 (0.62 to 1.66)0.0601.21 (0.71 to 2.06)0.469
  • *Statistically significant p values (<0.05).

  • SNP, single nucleotide polymorphism.