SNP (gene) | Genotype/allele | ORunadjusted (95% CI) | P value | ORadjusted (95% CI) | P value |
rs1205 (CRP) | Genotype | ||||
CC | 1 | 1 | |||
CT | 0.48 (0.24 to 0.95) | 0.036* | 0.51 (0.24 to 1.07) | 0.156 | |
TT | 0.88 (0.33 to 0.44) | 0.789 | 0.96 (0.32 to 2.85) | 1.000 | |
Allele | |||||
C | 1 | 1 | |||
T | 0.80 (0.51 to 1.26) | 0.327 | 0.83 (0.51 to 1.37) | 0.488 | |
rs5186 (AGTR1) | Genotype | ||||
AA | 1 | 1 | |||
AC | 0.45 (0.23 to 0.89) | 0.021* | 0.34 (0.15 to 0.72) | 0.010* | |
CC | 4.99 (0.56 to 44.44) | 0.149 | 4.59 (0.41 to 51.35) | 0.430 | |
Allele | |||||
A | 1 | 1 | |||
C | 0.79 (0.47 to 1.35) | 0.393 | 0.64 (0.36 to 1.14) | 0.134 | |
rs234706 (CBS) | Genotype | ||||
AA | 1 | 1 | |||
AG | 0.14 (0.05 to 0.41) | 0.000* | 0.21 (0.06 to 0.66) | 0.016* | |
GG | 0.56 (0.16 to 1.96) | 0.364 | 1.31 (0.32 to 5.39) | 1.000 | |
Allele | |||||
A | 1 | 1 | |||
G | 0.95 (0.61 to 1.47) | 0.803 | 1.20 (0.74 to 1.94) | 0.454 | |
rs602662 (FUT2) | Genotype | ||||
AA | 1 | 1 | |||
AG | 0.69 (0.28 to 1.68) | 0.415 | 0.73 (0.28 to 1.89) | 1.000 | |
GG | 0.23 (0.09 to 0.58) | 0.002* | 0.26 (0.09 to 0.71) | 0.018* | |
Allele | |||||
A | 1 | 1 | |||
G | 0.93 (0.53 to 1.63) | 0.796 | 0.45 (0.27 to 0.74) | 0.002* | |
rs1799889 (PAI-1) | Genotype | ||||
AA | 1 | 1 | |||
AG | 0.42 (0.19 to 0.91) | 0.028* | 0.44 (0.19 to 1.01) | 0.112 | |
GG | 0.26 (0.10 to 0.69) | 0.006* | 0.23 (0.08 to 0.66) | 0.012* | |
Allele | |||||
A | 1 | 1 | |||
G | 0.54 (0.34 to 0.84) | 0.006* | 0.51 (0.31 to 0.83) | 0.007* | |
rs1800871 (IL-10) | Genotype | ||||
AA | 1 | 1 | |||
AG | 0.34 (0.14 to 0.86) | 0.022* | 0.34 (0.12 to 0.94) | 0.076 | |
GG | 0.67 (0.27 to 1.66) | 0.384 | 0.66 (0.24 to 1.85) | 0.876 | |
Allele | |||||
A | 1 | 1 | |||
G | 0.95 (0.60 to 1.50) | 0.826 | 0.95 (0.58 to 1.57) | 0.860 | |
rs1801131 (MTHFR) | Genotype | ||||
GG | 1 | 1 | |||
GT | 0.27 (0.09 to 0.75) | 0.012* | 0.26 (0.08 to 0.79) | 0.034* | |
TT | 0.52 (0.19 to 1.41) | 0.200 | 0.50 (0.17 to 1.45) | 0.408 | |
Allele | |||||
G | 1 | 1 | |||
T | 0.93 (0.58 to 1.47) | 0.741 | 0.91 (0.55 to 1.49) | 0.715 | |
rs1801133 (MTHFR) | Genotype | ||||
AA | 1 | 1 | |||
AG | 0.29 (0.09 to 0.98) | 0.047* | 0.29 (0.08 to 1.10) | 0.070 | |
GG | 0.51 (0.16 to 1.63) | 0.255 | 0.66 (0.18 to 2.36) | 0.533 | |
Allele | |||||
A | 1 | 1 | |||
G | 1.02 (0.62 to 1.66) | 0.060 | 1.21 (0.71 to 2.06) | 0.469 |
*Statistically significant p values (<0.05).
SNP, single nucleotide polymorphism.