Table 4

Variable importance on random forest models and standard partial regression coefficient on multiple logistic regression models

	RF model 1		RF model 2		RF model 3		RF model 4		RF model 5		RF model 6		Total
	Variables	VI*	Variables	VI*	Variables	VI*	Variables	VI*	Variables	VI*	Variables	VI*	Variables	VI*
1	HbA1c_dif	100	HbA1c_dif	100	HbA1c_dif	100	HbA1c_dif	100	HbA1c	100	HbA1c	100	HbA1c_dif	100
2	HbA1c	66.8	HbA1c	41.6	FBG	53.3	HbA1c	96.6	HbA1c_dif	98.2	FBG	81.0	HbA1c	97.0
3	RF_dif	27.5	MCV_dif	28.7	HbA1c	50.8	FBG	87.2	FBG	81.9	HbA1c_dif	78.5	FBG	79.1
4	A/G_dif	27.0	FBG	28.4	FBG_dif	40.2	FBG_dif	65.0	FBG_dif	80.1	FBG_dif	62.7	FBG_dif	59.5
5	MCV_dif	25.2	RF_dif	25.7	MCV_dif	35.1	ALP	43.2	ALP	43.2	Weight	50.2	Weight	42.2
6	P-FEV1	23.3	MCHC_dif	25.1	CRP_dif	34.1	TC	43.1	Weight	41.7	ALP	42.9	ALP	41.2
7	P-FEV1_dif	23.2	FBG_dif	25.0	PLAT	33.3	weight	43.0	PLAT	40.0	TG	42.4	PLAT	38.7
8	GTP	22.7	P-FEV1_dif	25.0	FVC	33.3	CRP_dif	42.5	weight_dif	38.4	AST	40.8	CRP_dif	38.1
9	P-FVC_dif	22.4	P-FVC_dif	24.6	P-FEV1	32.6	PLAT	41.8	CK_dif	37.4	weight_dif	39.3	ALP_dif	38.0
10	CRP_dif	22.2	CRP_dif	24.4	ALP_dif	32.6	ChE	41.6	ALP_dif	37.2	ALP_dif	38.3	TG	37.7
	MLR model 1		MLR model 2		MLR model 3		MLR model 4		MLR model 5		MLR model 6		Total
	Variables	SRC*	Variables	SRC*	Variables	SRC*	Variables	SRC*	Variables	SRC*	Variables	SRC*	Variables	SRC*
1	MCH	100.0	HbA1c_dif	100.0	MCH	100.0	MCH	100.0	MCH	100.0	Ht	100.0	MCH	100.0
2	MCV	82.5	HbA1c	84.6	MCHC	53.2	MCV	61.9	MCV	64.7	Hb	80.0	MCV	72.6
3	MCHC	34.5	FBG	81.3	MCV	52.7	MCHC	46.2	MCHC	46.2	Hb_dif	32.9	MCHC	43.6
4	HbA1c	33.0	TC	75.7	Ht	46.5	RCC	30.0	FEV1	33.6	Ht_dif	30.9	Ht	43.2
5	Ht_dif	32.9	ALB_dif	71.4	RCC	43.7	Ht	29.1	MCH_dif	33.0	RCC	29.6	HbA1c_dif	39.1
6	TC	30.7	MCH	67.3	FVC	42.8	Hb_dif	24.6	FVC	29.5	MCHC	23.6	HbA1c	33.6
7	LDL-C	26.2	LDL-C	63.3	MCH_dif	41.5	RCC_dif	20.5	MCV_dif	28.3	MCV	18.8	FBG	32.6
8	HbA1c_dif	24.7	MCV	58.4	MCV_dif	39.4	MCV_dif	14.8	MCHC_dif	25.9	MCHC_dif	14.9	TC	29.5
9	FBG	20.6	HDL-C	51.1	HbA1c_dif	37.3	HbA1c_dif	12.8	Ht	24.4	HbA1c	8.2	RCC	27.1
10	HDL-C	19.4	A/G_dif	43.6	FBG	31.9	Cl	10.6	RCC	23.1	TC	6.7	LDL-C	25.1

*Variable importance and standard partial regression coefficient are expressed as percentages. We set the degree of most influential variable in each model as 100% (SRC is converted to an absolute value because it can take a negative value).
A/G, albumin/globulin ratio; CRP, C reactive protein; dif, Change value from the previous year ; FBG, fasting blood glucose; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; GTP, glutamyl transpeptidase; Hb, haemoglobin; HbA1c, glycated haemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; Ht, haematocrit; MCHC, mean corpuscular haemoglobin concentration; MLR, Multiple Logistic Regression; PLAT, platelet; RCC, red cell count; RF, Random Forest; SPRC, Standard Regression Coefficient; TC, total cholesterol; VI, Variable Importance.