Variables used in random forest method and multiple logistic regression models
| Objective variable | ||||
| Model 1 (≥0%) | 1 | HbA1c increase of ≥0% from previous year† | 0 | HbA1c increase of not ≥0% from previous year‡ |
| Model 2 (≥0.2%) | 1 | HbA1c increase of ≥0.2% from previous year† | 0 | HbA1c increase of not ≥0.2% from previous year‡ |
| Model 3 (≥0.4%) | 1 | HbA1c increase of ≥0.4% from previous year† | 0 | HbA1c increase of not ≥0.4% from previous year‡ |
| Model 4 (≥0.6%) | 1 | HbA1c increase of ≥0.6% from previous year† | 0 | HbA1c increase of not ≥0.6% from previous year‡ |
| Model 5 (≥0.8%) | 1 | HbA1c increase of ≥0.8% from previous year† | 0 | HbA1c increase of not ≥0.8% from previous year‡ |
| Model 6 (≥1.0%) | 1 | HbA1c increase of ≥1.0% from previous year† | 0 | HbA1c increase of not ≥1.0% from previous year‡ |
| Explanatory variables (97 variables in total) | ||||
| Single-year value and change from previous year (92 (46+46) in total) | Weight, BMI, body fat, WCC, RCC, Hb, Ht, MCV, MCH, MCHC, PLAT, TP, ALB, A/G, ChE, T-Bil, D-Bil, I-Bil, ALP, LAP, GTP, LDH, AST, ALT, BUN, CRE, UA, Na, K, Cl, Ca, CK, TG, TC, LDL-C, HDL-C, FBG, HbA1c, S-BP, D-BP, FVC, FEV1, P-FVC, P-FEV1, CRP, RF | |||
| Only single-year value (five in total) | Gender, age, height, drink*, smoke* | |||
*Drink: drinking more than twice a week (1) or not (0), smoke: Having current smoking habit (1) or not (0).
†the upper limit of HbA1c increase is +5.6%.
‡the lower limit of HbA1c increase is −2.0%.
A/G, albumin/globulin ratio; ALB, albumin; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; Ca, calcium; ChE, cholinesterase; CK, creatine kinase; Cl, chloride; CRE, creatinine; CRP, C reactive protein; D-Bil, direct bilirubin; D-BP, diastolic blood pressure; FBG, fasting blood glucose; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; GTP, glutamyl transpeptidase; Hb, haemoglobin; HbA1c, glycated haemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; Ht, haematocrit; I-Bil, Indirect bilirubin; LAP, Leucine aminopeptidase; LDH, Lactate dehydrogenase; LDL-C, low-density lipoprotein cholesterol; MCH, mean corpuscular haemoglobin; MCHC, mean corpuscular haemoglobin concentration; MCV, mean corpuscular volume; Na, sodium; P-FEV1, forced expiratory volume ％ in one 1s; P-FVC, forced vital capacity %; PLAT, platelet; RCC, red cell count; RF, rheumatoid factor; S-BP, systolic blood pressure; T-Bil, total bilirubin; TC, total cholesterol; TG, triglyceride; TP, total protein; UA, urinary acid; WCC, white cell count.