First author, year, country | Weight results | Significance | Other outcome measures | |||
BP | Blood lipids | Waist circumference | HbA1c | |||
Bryce, 2017,23 USA | Baseline: 208.3 lbs (94.68 kg) Follow-up: 209.0 lbs (95 kg) Percentage change: +0.3 | No difference between baseline and follow-up observed (p>0.05) | No significant change from baseline to follow-up for SBP (p=0.70) or DBP (p=0.17) | NA | NA | Significant reduction in mean HbA1c from 9.54% to 8.83% (t-score=3.54, p=0.001) |
Narotzki, 2013,22 Israel | Baseline: INT: 76.8±10.3 kg CON: 76.2±7.6 kg Follow-up: INT: 73.4±9.9 kg CON: 74.5±8.0 kg Percentage change: INT: −4.4 CON: −2.2 | No difference between groups at follow-up (p>0.05); both groups observed significant weight loss (INT mean −3.4 kg, p=0.004; CON mean −1.7 kg, p=0.004) | No significant difference between the groups at follow-up for SBP (p=0.409) or DBP (p=0.675); no significant changes within either group | No significant difference between groups at follow-up for TG (p=0.233), LDL-C (p=0.98) or HDL-C (p=0.671); no significant changes within either group | No significant difference between groups at baseline or follow-up (p>0.05). INT men and women observed a significant reduction (men: −3.8±3.4%, p=0.026; women: −11.2±3.1%, p=0.005) | No significant difference between the groups at baseline or follow-up (p>0.05); no significant change within either group |
Ahrens, 2003,21 USA | Baseline: 81.9±11.1 kg 12 weeks: 77.0±10.2 kg Percentage change: −6 | Mean change −4.9 kg, p<0.0001 | Mean change 12 weeks SBP −5.91 mm Hg (−4.56%), DBP −4.16 mm Hg (−5.79%). Significance of changes NR | Mean change 12 weeks TC −11.95 mg/dL (−5.87%); TG −0.08 mg/dL (−1.73%); LDL-C −8.86 mg/dL (−7.08%); HDL-C −0.19 mg/dL (−0.36%). Significance of changes NR | Mean change 12 weeks −5.31 cm (−5.96%). Significance of change NR | NA |
Isaacs, 1984,24 UK | Baseline: 88.93±15.5 kg Follow-up: 82.27±14.9 kg Percentage change: −7.5 | Significance of change NA | Those who completed the trial and had initial DBP >90 mm Hg observed a significant reduction in mean BP (baseline 158/101, follow-up 145/89, p<0.0001) | NA | NA | NA |
BP, blood pressure; CON, control; DBP, diastolic blood pressure; HbA1c, glycated haemoglobin; HDL-C, high-density lipoprotein cholesterol; INT, intervention; LDL-C, low-density lipoprotein cholesterol; NA, not assessed; NR, not reported; SBP, systolic blood pressure; TC, total cholesterol; TG, triglycerides.