Summary relative risks for subtypes of fruits and type 2 diabetes, high versus low and dose–response analyses
Fruit subtype | High versus low analysis | Dose–response analysis | |||||||||||
n | RR (95% CI) | I2 | Ph | Egger | References | n | Increment | RR (95% CI) | I2 | Ph | Egger | References | |
Apples | 3 | 0.79 (0.72 to 0.87) | 0 | 0.52 | 0.03 | 10 25 26 | 2 | Per 100 g/day | 0.91 (0.88 to 0.95) | 0 | 0.87 | – | 10 26 |
Apples and pears | 5 | 0.88 (0.77 to 1.00) | 74.7 | 0.003 | 0.21 | 21 51 61 | 4 | Per 100 g/day | 0.90 (0.83 to 0.97) | 38.4 | 0.18 | 0.98 | 21 61 |
Bananas | 5 | 0.97 (0.84 to 1.13) | 70.5 | 0.009 | 0.80 | 10 21 61 | 5 | Per 100 g/day | 0.93 (0.80 to 1.08) | 84.4 | <0.0001 | 0.72 | 10 21 61 |
Berries | 5 | 0.89 (0.72 to 1.10) | 79.6 | 0.001 | 0.27 | 8 21 22 | 5 | Per 50 g/day | 0.94 (0.77 to 1.14) | 86.7 | <0.0001 | 0.76 | 8 21 22 |
Blueberries | 3 | 0.76 (0.67 to 0.87) | 0 | 0.49 | 0.54 | 21 | 3 | Per 50 g/day | 0.60 (0.49 to 0.73) | 0 | 0.59 | 0.70 | 21 |
Cantaloupe | 3 | 1.11 (1.02 to 1.20) | 0 | 0.57 | 0.37 | 21 | 3 | Per 100 g/day | 1.18 (1.04 to 1.34) | 0 | 0.82 | 0.18 | 21 |
Citrus fruits | 6 | 1.04 (0.98 to 1.11) | 0 | 0.92 | 0.79 | 6 9 10 12 14 15 | 6 | Per 100 g/day | 1.02 (0.96 to 1.08) | 46.9 | 0.09 | 0.29 | 6 9 10 12 14 15 |
Fruit drinks | 6 | 1.28 (1.07 to 1.52) | 62.0 | 0.02 | 0.37 | 22 40 63–66 | 7 | Per 250 g/day | 1.13 (1.01 to 1.27) | 66.4 | 0.007 | 0.19 | 22 40 57 63–66 |
Fruit juice | 8 | 1.09 (1.02 to 1.18) | 44.2 | 0.08 | 0.08 | 12 21 23 29 50 59 | 8 | Per 250 g/day | 1.08 (1.00 to 1.16) | 68.7 | 0.002 | 0.78 | 12 21 23 29 50 59 |
100% fruit juice | 4 | 0.95 (0.84 to 1.08) | 0 | 0.64 | 0.69 | 12 29 50 59 | 4 | Per 250 g/day | 0.97 (0.91 to 1.03) | 0 | 0.86 | 0.31 | 12 29 50 59 |
Grapefruit | 3 | 0.94 (0.81 to 1.10) | 48.4 | 0.14 | 0.75 | 21 | 3 | Per 100 g/day | 0.90 (0.82 to 0.99) | 4.6 | 0.35 | 0.44 | 21 |
Grapes and raisins | 4 | 0.83 (0.76 to 0.91) | 0 | 0.78 | 0.98 | 10 21 | 4 | Per 50 g/day | 0.74 (0.66 to 0.83) | 0 | 0.69 | 0.45 | 10 21 |
Oranges | 4 | 0.99 (0.93 to 1.06) | 0 | 0.51 | 0.35 | 10 21 | 4 | Per 100 g/day | 0.97 (0.92 to 1.04) | 0 | 0.89 | 0.53 | 10 21 |
Peaches, plums and apricots | 3 | 0.91 (0.80 to 1.04) | 2.6 | 0.36 | 0.72 | 21 | 3 | Per 100 g/day | 0.89 (0.73 to 1.09) | 44.9 | 0.16 | 0.33 | 21 |
Prunes | 3 | 0.94 (0.80 to 1.11) | 34.0 | 0.22 | 0.63 | 21 | 3 | Per 100 g/day | 0.73 (0.52 to 1.02) | 0 | 0.45 | 0.78 | 21 |
Strawberries | 3 | 1.11 (0.90 to 1.38) | 35.2 | 0.21 | 0.08 | 21 | 3 | Per 50 g/day | 1.10 (0.88 to 1.38) | 76.5 | 0.01 | 0.24 | 21 |
Watermelon | 2 | 1.06 (0.95 to 1.20) | 0 | 0.64 | – | 9 10 | 2 | Per 100 g/day | 1.05 (1.00 to 1.11) | 0 | 0.72 | – | 9 10 |
n, number of studies; Ph, p value for heterogeneity; RR, relative risk.