Table 3

Effect of group (Ref. intervention group) on the metabolic risk profile (adjusted for sex, baseline values and risk group at baseline of the respective variable); forced enter approach

	Change after
	8 weeks				6 months				12 months				18 months				24 months
	ß	SE	P value	R²	ß	SE	P value	R²	ß	SE	P value	R²	ß	SE	P value	R²	ß	SE	P value	R²
Anthropometrics
BMI (kg/m²)	−0.39	0.12	0.002	0.094	−0.26	0.22	0.229	0.030	−0.66	0.23	0.005	0.086	−0.71	0.30	0.021	0.080	−0.38	0.36	0.299	0.067
WC (cm)	2.00	0.89	0.027	0.049	2.01	1.05	0.059	0.023	−0.28	1.07	0.797	−0.005	−0.11	1.19	0.928	0.012	1.91	1.21	0.118	0.065
Blood parameters
Lipids
Total-C (mg/dL)	−21.94	4.81	0.000	0.316	−11.42	8.44	0.180	0.061	−12.24	4.84	0.013	0.087	−7.16	5.04	0.160	−0.026	−1.05	6.25	0.867	0.038
LDL-C (mg/dL)	−19.10	4.40	0.000	0.252	−13.37	4.51	0.004	0.241	−10.87	4.16	0.011	0.142	−8.84	4.59	0.059	0.007	−2.85	5.97	0.635	0.088
HDL-C (mg/dL)	−6.39	1.61	0.000	0.253	−3.72	2.14	0.085	0.162	−2.14	1.83	0.246	−0.005	3.58	2.39	0.138	0.035	3.21	2.18	0.146	0.080
TG (mg/dL)	4.85	6.56	0.461	0.502	14.71	13.23	0.269	0.065	−0.99	6.40	0.878	0.465	2.99	6.94	0.668	0.534	11.49	8.23	0.167	0.662
Diabetic parameters
FG (mg/dL)	8.57	1.93	0.000	0.527	10.63	3.05	0.001	0.272	12.29	2.37	0.000	0.414	11.34	2.21	0.000	0.645	11.14	3.09	0.001	0.268
HbA1c (%)	0.20	0.03	0.000	0.326	0.36	0.04	0.000	0.459	0.35	0.07	0.000	0.303	−0.02	0.06	0.697	0.525	0.20	0.09	0.023	0.066
FI (µU/mL)	−0.44	0.83	0.601	0.080	−2.26	1.35	0.097	0.015	0.78	0.91	0.393	0.015	2.13	1.01	0.038	0.173	2.26	1.08	0.040	0.138
HOMA-IR	0.17	0.24	0.495	0.308	−0.16	0.35	0.646	0.250	0.52	0.27	0.059	0.295	0.93	0.29	0.002	0.532	0.89	0.30	0.004	0.547
Vital parameters
SBP (mm Hg)	−0.48	2.33	0.838	0.288	−0.70	2.75	0.799	0.277	−4.28	2.65	0.110	0.374	5.34	3.32	0.113	0.351	−1.01	3.63	0.782	0.273
DBP (mm Hg)	−0.23	1.35	0.864	0.249	0.04	1.49	0.980	0.285	−4.38	1.53	0.005	0.406	0.10	1.76	0.956	0.229	−1.78	1.69	0.297	0.381

Constants (ß₀) and its SE are not shown and numbers are rounded to two decimals to improve readability; an extended version of the table can be found in appendix (online supplemental table S-1, online supplemental figure S-2, online supplemental table S-3.
Bold p-values ≤0.05
ß, effect size for group; BMI, body mass index; DBP, diastolic blood pressure; FG, fasting glucose; FI, fasting insulin; HbA1c, glycated haemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, Homeostasis Model Assessment-insulin resistance; LDL-C, low-density lipoprotein cholesterol; R², corrected R²; SBP, systolic blood pressure; TG, triglycerides; TOTAL-C, total cholesterol; WC, waist circumference.