Incorporation of risk of bias in the synthesis of results
| Number of reviews (%) n=131 (reviews that assessed risk of bias) | |
| Did the review exclude studies at high risk of bias from either the review or the synthesis? | |
| Studies at high risk of bias were excluded from the review | 1 (0.7) |
| Studies at high risk of bias were excluded from the meta-analysis | 2 (1.5) |
| Studies were not excluded from either the review or synthesis based on risk of bias | 128 (97.7) |
| Among reviews that assessed performed meta-analysis (n=101; 77.1%), was a subgroup analysis or meta-regression based on risk of bias conducted? | |
| Yes; based on overall risk of bias | 28 (27.7) |
| Yes; based on specific risk of bias items/domains | 7 (6.9) |
| No | 66 (65.3) |
| Among reviews that conducted a subgroup analysis or meta-regression based on risk of bias (n=35; 26.7%), was the subgroup analysis or meta-regression statistically significant? | |
| Yes | 5 (14.2) |
| No | 22 (62.8) |
| Not reported | 8 (22.8) |