Table 3

Effect of group (Ref. intervention group) on the metabolic risk profile (adjusted for sex, baseline values and risk group at baseline of the respective variable); forced enter approach


Change after
8 weeks6 months12 months18 months24 months
ßSEP valueßSEP valueßSEP valueßSEP valueßSEP value
Anthropometrics
 BMI (kg/m²)−0.390.12 0.002 0.094−0.260.220.2290.030−0.660.23 0.005 0.086−0.710.30 0.021 0.080−0.380.360.2990.067
 WC (cm)2.000.89 0.027 0.0492.011.050.0590.023−0.281.070.797−0.005−0.111.190.9280.0121.911.210.1180.065
Blood parameters
Lipids
 Total-C (mg/dL)−21.944.81 0.000 0.316−11.428.440.1800.061−12.244.84 0.013 0.087−7.165.040.160−0.026−1.056.250.8670.038
 LDL-C (mg/dL)−19.104.40 0.000 0.252−13.374.51 0.004 0.241−10.874.16 0.011 0.142−8.844.590.0590.007−2.855.970.6350.088
 HDL-C (mg/dL)−6.391.61 0.000 0.253−3.722.140.0850.162−2.141.830.246−0.0053.582.390.1380.0353.212.180.1460.080
 TG (mg/dL)4.856.560.4610.50214.7113.230.2690.065−0.996.400.8780.4652.996.940.6680.53411.498.230.1670.662
Diabetic parameters
 FG (mg/dL)8.571.93 0.000 0.52710.633.05 0.001 0.27212.292.37 0.000 0.41411.342.21 0.000 0.64511.143.09 0.001 0.268
 HbA1c (%)0.200.03 0.000 0.3260.360.04 0.000 0.4590.350.07 0.000 0.303−0.020.060.6970.5250.200.09 0.023 0.066
 FI (µU/mL)−0.440.830.6010.080−2.261.350.0970.0150.780.910.3930.0152.131.01 0.038 0.1732.261.08 0.040 0.138
 HOMA-IR0.170.240.4950.308−0.160.350.6460.2500.520.270.0590.2950.930.29 0.002 0.5320.890.30 0.004 0.547
Vital parameters
 SBP (mm Hg)−0.482.330.8380.288−0.702.750.7990.277−4.282.650.1100.3745.343.320.1130.351−1.013.630.7820.273
 DBP (mm Hg)−0.231.350.8640.2490.041.490.9800.285−4.381.53 0.005 0.4060.101.760.9560.229−1.781.690.2970.381
  • Constants (ß0) and its SE are not shown and numbers are rounded to two decimals to improve readability; an extended version of the table can be found in appendix (online supplemental table S-1, online supplemental figure S-2, online supplemental table S-3.

  • Bold p-values ≤0.05

  • ß, effect size for group; BMI, body mass index; DBP, diastolic blood pressure; FG, fasting glucose; FI, fasting insulin; HbA1c, glycated haemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, Homeostasis Model Assessment-insulin resistance; LDL-C, low-density lipoprotein cholesterol; R², corrected R²; SBP, systolic blood pressure; TG, triglycerides; TOTAL-C, total cholesterol; WC, waist circumference.