Table 2

Comparison of Jarlsberg and Camembert cheese in development of osteocalcin variables and bone markers and the vitamin K2 vitamers during 6 weeks of daily cheese intake. The results are expressed by mean values with SD in bracket and 95% CIs

VariablesBaselineWeek 6Week 6—baselineP values between groups
Jarlsberg (n=41)Camembert
(n=25)
Jarlsberg
(n=41)
Camembert
(n=25)
Jarlsberg
(n=41)
Camembert
(n=25)
cOC=carboxylated
osteocalcin (ng/mL)
11.2 (9.0)16.1 (18.3)15.3 (9.5)14.9 (15.0)4.1 (6.8)−1.2 (9.7)p<0.01
8.4 to 14.18.6 to 23.712.3 to 18.38.7 to 21.02.0 to 6.2−5.3 to 2.8
ucOC=undercarboxylated osteocalcin (ng/mL)10.2 (10.4)7.2 (5.4)10.3 (12.9)6.6 (5.0)0.2 (6.0)−0.6 (1.9)p=0.47
6.9 to 13.55.0 to 9.46.3 to 14.44.5 to 8.6−1.7 to 2.1−1.4 to 0.2
RO =carboxylated/
undercarboxylated
1.47 (0.94)1.86 (1.14)2.19 (1.31)2.09 (1.34)0.72 (0.90)0.23 (1.09)p=0.03
1.17 to 1.761.39 to 2.331.78 to 2.601.54 to 2.640.44 to 1.01−0.26 to 0.65
PINP=procollagen (ng/mL)61.1 (27.5)61.4 (24.1)*69.1 (34.9)58.4 (21.7)8.1 (13.9)−1.3 (11.4)*p<0.01
52.4 to 69.751.0 to 71.858.1 to 80.249.4 to 67.43.7 to 12.4−6.2 to 3.6
CTX=collagen I (ng/mL)0.29 (0.13)0.27 (0.17)*0.27 (0.15)0.28 (0.15)−0.02 (0.13)0.02 (0.15)*p=0.27
0.25 to 0.330.19 to 0.340.22 to 0.320.22 to 0.34−0.06 to 0.02−0.04 to 0.08
MK-7
(ng/mL)
0.12 (0.07)0.21 (0.17)0.15 (0.06)0.18 (0.08)0.04 (0.07)−0.03 (0.15)p=0.02
0.09 to 0.140.14 to 0.280.14 to 0.170.15 to 0.220.02 to 0.06−0.09 to 0.04
MK-8
(ng/mL)
0.09 (0.07)0.12 (0.08)0.22 (0.11)0.07 (0.06)0.12 (0.10)−0.05 (0.06)p<0.01
0.07 to 0.120.09 to 0.150.18 to 0.250.04 to 0.090.09 to 0.16−0.08 to 0.03
MK-9
(ng/mL)
0.09 (0.09)0.11 (0.07)0.21 (0.09)0.05 (0.04)0.12 (0.11)−0.06 (0.07)p<0.01
0.06 to 0.120.08 to 0.140.18 to 0.240.04 to 0.070.09 to 0.16−0.09 to −0.03
MK-9(4H)
(ng/mL)
0.08 (0.06)0.10 (0.07)0.14 (0.07)0.10 (0.05)0.06 (0.05)0.00 (0.05)p<0.01
0.06 to 0.090.06 to 0.090.12 to 0.160.08 to 0.120.05 to 0.08−0.02 to 0.02
1.15 to 1.261.11 to 1.261.18 to 1.291.10 to 1.22−0.02 to 0.09−0.08 to 0.03
  • *Two baseline blood samples in the Camembert group were lost and reduced the sample to 23 for estimation and comparison of the development in PINP and CTX.

  • cOC, carboxylation osteocalcin ; CTX, C-telopeptide type I collagen ; MK, menaquinone; PINP, procollagen type 1 N-terminal propeptide ; Ro, osteocalcin ratio; ucOC, undercarboxylated osteocalcin.