The risk of incident hypertension within 10 years following delivery by quintile intake of sucrose-sweetened beverages as percent energy: MoBa Cohort Study (n=60 027)
Entire cohort quintiles SSB, %E | Participants, n | Cases, n | Model 1* HR (95% CI) | Model 2† HR (95% CI) | Model 3‡ HR (95% CI) |
Q1 | 12 005 | 312 | Referent | Referent | Referent |
Q2 | 12 004 | 224 | 0.76 (0.64 to 0.90) | 0.88 (0.73 to 1.05) | 0.88 (0.73 to 1.05) |
Q3 | 12 006 | 279 | 0.93 (0.79 to 1.09) | 1.05 (0.89 to 1.25) | 1.04 (0.88 to 1.23) |
Q4 | 12 006 | 279 | 0.93 (0.79 to 1.09) | 1.01 (0.85 to 1.19) | 0.98 (0.83 to 1.17) |
Q5 | 12 006 | 386 | 1.27 (1.09 to 1.47) | 1.25 (1.07 to 1.47) | 1.20 (1.02 to 1.42) |
Sensitivity analyses | |||||
Non-smokers | |||||
Q1 | 9952 | 238 | Referent | Referent | Referent |
Q2 | 10 187 | 195 | 0.85 (0.70 to 1.03) | 0.97 (0.80 to 1.18) | 0.96 (0.79 to 1.17) |
Q3 | 10 099 | 229 | 0.99 (0.82 to 1.18) | 1.10 (0.91 to 1.33) | 1.07 (0.89 to 1.30) |
Q4 | 9637 | 213 | 0.96 (0.80 to 1.16) | 0.99 (0.82 to 1.21) | 0.95 (0.78 to 1.16) |
Q5 | 8673 | 274 | 1.34 (1.12 to 1.59) | 1.29 (1.08 to 1.55) | 1.20 (0.99 to 1.45) |
Low weight gain§ | |||||
Q1 | 8730 | 198 | Referent | Referent | Referent |
Q2 | 9096 | 162 | 0.82 (0.67 to 1.01) | 0.94 (0.76 to 1.16) | 0.93 (0.75 to 1.15) |
Q3 | 9145 | 193 | 0.95 (0.78 to 1.16) | 1.07 (0.87 to 1.31) | 1.05 (0.85 to 1.28) |
Q4 | 8953 | 189 | 0.95 (0.78 to 1.16) | 1.00 (0.81 to 1.23) | 0.97 (0.79 to 1.20) |
Q5 | 8465 | 275 | 1.42 (1.18 to 1.71) | 1.36 (1.13 to 1.65) | 1.30 (1.06 to 1.58) |
Nulliparous | |||||
Q1 | 5209 | 104 | Referent | Referent | Referent |
Q2 | 5480 | 84 | 0.82 (0.61 to 1.09) | 0.92 (0.68 to 1.24) | 0.92 (0.68 to 1.24) |
Q3 | 5427 | 88 | 0.87 (0.66 to 1.16) | 0.96 (0.71 to 1.30) | 0.95 (0.70 to 1.29) |
Q4 | 5100 | 97 | 1.02 (0.77 to 1.35) | 1.09 (0.81 to 1.46) | 1.06 (0.79 to 1.43) |
Q5 | 4807 | 117 | 1.30 (0.99 to 1.70) | 1.28 (0.97 to 1.70) | 1.22 (0.91 to 1.64) |
First 90 months of follow-up | |||||
Q1 | 12 005 | 279 | Referent | Referent | Referent |
Q2 | 12 004 | 205 | 0.76 (0.64 to 0.92) | 0.89 (0.73 to 1.07) | 0.88 (0.73 to 1.07) |
Q3 | 12 006 | 248 | 0.93 (0.78 to 1.10) | 1.05 (0.88 to 1.25) | 1.04 (0.87 to 1.24) |
Q4 | 12 006 | 243 | 0.93 (0.78 to 1.10) | 1.00 (0.83 to 1.20) | 0.98 (0.82 to 1.18) |
Q5 | 12 006 | 347 | 1.35 (1.15 to 1.58) | 1.32 (1.11 to 1.56) | 1.27 (1.06 to 1.51) |
*Maternal age at delivery (years), total energy intake (kcal/day) evaluated in Cox proportional hazards analyses.
†Maternal age at delivery (years), total energy intake (kcal/day), body mass index, daily smoking prior to pregnancy, parity, diabetes mellitus (prior or during pregnancy or type unspecified), gestational hypertension (with or without proteinuria), preterm delivery (<37 weeks gestation) and physical activity (>3 hours, <3 hours per/week, missing).
‡Model 2 covariates plus intake of dietary fibre (g/day) and added sugar from food as percent energy.
§Low weight gain between prepregnancy and 6 months postpartum weight (<7 kg).
%E, as percent of total energy; Q, quintile; SSB, sugar-sweetened beverage.