Table 2

Adverse events arising during low energy diet (LED) and dulaglutide intervention phase

BaselineEnd of 2-week run-inAfter 2-week LEDEnd of trial
Number of participants reporting ≥1 symptom5101310
Symptoms reportedN%*N%*N%*N%*
Nausea210.5736.8315.800.0
Vomiting15.315.300.000.0
Abdominal pain210.5421.1210.500.0
Diarrhoea315.8526.3631.600.0
Constipation15.300.0421.115.3
Dizziness210.5421.1421.1210.5
Heartburn00.0210.515.300.0
Headaches210.5526.3315.8315.8
Mood changes210.5315.8210.515.3
Cold sensitivity210.5210.5421.1421.1
Hair loss15.300.0210.5315.8
Fatigue315.8736.8421.115.3
Total symptoms reported21403515
  • *Percentages calculated from total number of participants, not just of those reporting adverse effects.