Parameter | Time point | Erythritol group (n=14) | Xylitol group (n=14) | Control group (n=14) | Time effect (P value) | Treatment effect (P value) |
Liver volume (L) | Preintervention | 1.70±0.40 | 1.81±0.47 | 1.72±0.30 | 0.307 | 0.564 |
Postintervention | 1.70±0.47 | 1.89±0.52 | 1.70±0.32 | |||
Liver fat percentage (%) | Preintervention | 9.5±7.8 | 7.3±6.6 | 6.1±7.3 | 0.436 | 0.892 |
Postintervention | 8.7±7.6 | 7.3±7.5 | 6.0±6.5 | |||
VAT volume (L) | Preintervention | 4.64±2.62 | 3.98±1.85 | 4.21±1.53 | 0.216 | 0.583 |
Postintervention | 5.11±3.00 | 4.39±2.03 | 4.32±1.72 | |||
SAT volume (L) | Preintervention | 13.06±3.73 | 12.84±2.71 | 13.27±4.32 | 0.300 | 0.995 |
Postintervention | 12.96±4.22 | 13.07±2.71 | 13.48±4.57 | |||
Triglycerides (mmol/L) | Preintervention | 1.9±1.3 | 1.4±0.7 | 2.2±2.1 | 0.158 | 0.837 |
Postintervention | 1.6±1.0 | 1.7±1.0 | 1.2±0.5 | |||
Total cholesterol (mmol/L) | Preintervention | 5.4±1.4 | 4.8±0.9 | 4.7±1.0 | 0.489 | 0.365 |
Postintervention | 5.0±1.1 | 4.8±1.1 | 4.6±0.9 | |||
HDL-cholesterol (mmol/L) | Preintervention | 1.8±1.8 | 1.4±0.3 | 1.2±0.3 | 0.240 | 0.364 |
Postintervention | 1.3±0.4 | 1.3±0.2 | 1.2±0.3 | |||
LDL-cholesterol (mmol/L) | Preintervention | 3.0±0.9 | 3.0±0.5 | 3.1±0.7 | 0.038* | 0.943 |
Postintervention | 2.9±0.7 | 2.9±0.6 | 2.9±0.9 |
Linear mixed effect model with subsequent Šidak test.
*Significant with p<0.05.
HDL, high-density lipoprotein; LDL, low-density lipoprotein; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue.