Table 5

Efficacy analysis (per protocol)—showing mean at randomisation baseline and mean change at week 16 along with 95% CI (in parenthesis): a randomised controlled potassium diet intervention study in patients (n=172) of rheumatoid arthritis (RA) on standard care [A: potassium-rich diet; B; potassium-rich diet plus potassium food supplement; C; routine diet)

Variable (normal range)A (n=52)B (n=50)C (n=53)P*
BaselineMean changeBaselineMean changeBaselineMean change
Pain visual analogue score (0–10 mm)5.45, (5.18, 5.66)−1.31 (-2.19, –0.43)5.42 (5.19, 5.65)−2.23 (–2.99, –1.48)5.26 (5.01, 5.52)−1.25 (–2.03, –0.46)0.03
Swollen joint count (0–66)2.36, (1.76, 2.99)−1.76 (–2.49, –1.03)2.46 (1.84, 3.15)−0.74 (–2.4, 0.92)2.5 (1.51, 3.78)−1.66 (–3.06, –0.25)0.27
Painful tender joint count (0–68)11.19 (8.65, 13.74)−8.63 (–12.17, –5.1)13.11 (10.21, 16.01)−8.88 (–12.98, 4.77)11.96 (8.82, 14.46)−6.09 (–11.11, –1.07)0.42
Patient Global Assess (grade 1–5)2.09 (1.91, 2.22)−0.55 (–0.91, 0.2)2.12 (1.89, 2.34)−0.6 (–0.98, –0.21)1.96 (1.79, 2.13)−0.26 (–0.6, 0.07)0.15
Physician Global Assess (grade 1–5)1.36 (1.22, 1.49)−0.42 (–0.58, –0.27)1.36 (1.19, 1.53)−0.43 (–0.63, – 0.19)1.41 (1.25, 1.55)−0.50 (–0.69, –0.30)0.84
Health assess Questionnaire (0–24)5.32 (4.50, 6.14)−1.94 (–3.22, 0.66)5.11 (4.18, 6.05)−2.62 (–4.04, –1.2)4.60 (3.86, 5.14)−0.86 (–2.21, 0.48)0.05
General Health VAS (0–100)51.03 (47.64, 54.42)13.61 (5.91, 21.31)51.78 (47.32, 55.66)14.82 (5.90, 23.73)50.39 (48.24, 53.58)10.92 (3.19, 18.65)0.61
RA Pain Scale (0–144)61.96 (53.13, 70.79)−16.80 (–29.17, 4.44)56 (47.53, 64.46)−12.5 (–27.82, 2.82)63.37 (55.02, 70.43)−24.09 (–36.83, –11.35)0.26
Short Form 36—Physical score42.24 (40.18 43.89)1.75 (-1.17, 4.69)41.75 (39.66, 43.31)3.03 (0.39, 6.45)43.39 (41.85, 44.70)0.07 (–2.17, 2.31)0.15
Short Form 36—Mental score40.57 (38.01, 42.39)2.34 (–1.05, 5.74)41.57 (39.06, 43.05)1.44 (–1.71, 4.61)40.49 (38.86, 42.73)2.81 (–0.55, 6.18)0.73
ESR (mm fall end 1st hour)70.48 (72.73, 78.51)−8.05 (–17.85, 1.7)68.76 (61.51, 76.56)−11.66 (–22.30, –1.01)64.05 (57.67, 72.50)−8.66 (–17.77, 0.4)0.76
C reactive protein (mg/dlL)31.66 (23.17, 44.53)−18.31 (–33.10, 3.5)26.89 (17.79, 35.43)−8.33 (–18.45, –1.8)23.23 (15.21, 35.98)−8.57 (–23.77, 6.6)0.33
Disease Activity Score 28 (ESR)4.85 (4.67, 5.16)−1.38 (–1.81,–0.9)4.97 (4.73, 5.31)−1.22 (–1.76, –0.68)4.84 (4.60, 5.07)−1.05 (–1.62, –0.47)0.46
  • *Analysis of variance; significant p<0.05, two-sided; see text for details.

  • ESR, erythrocyte sedimentation rate; n, number of patients.