Variable | Hp1-1 (N=473) | Hp2-1 (N=1506) | Hp2-2 (N=1197) | P value* |
Age (years) | 62.5 (10.8) | 62.8 (10.6) | 62.8 (10.7) | 0.851 |
Female sex (%) | 29.6 | 30.1 | 30.4 | 0.947 |
BMI (kg/m2) | 27.5 (4.14) | 27.4 (3.97) | 27.6 (4.2) | 0.630 |
Total-C (mg/dL) | 193 (40.8) | 191 (38.1) | 193 (39.9) | 0.522 |
LDL-C (mg/dL) | 118 (36.4) | 116 (33.3) | 116 (34.7) | 0.502 |
HDL-C (mg/dL) | 38.6 (11) | 38.3 (10.3) | 39.2 (11.3) | 0.078 |
Apo-A1 (mg/dL) | 130 (25.4) | 129 (24.1) | 130 (26) | 0.214 |
Apo-A2 (mg/dL) | 41.6 (9.21) | 41.2 (9.17) | 42.0 (9.89) | 0.135 |
Cholesterol efflux (%) | 86.3 (27) | 89.4 (27.5) | 86.3 (26.6) | 0.006 |
FC/CE | 0.371 (0.351–0.397) | 0.374 (0.352–0.399) | 0.374 (0.352–0.4) | 0.531 |
CETP (µg/mL) | 1.07 (0.82–1.43) | 1.07 (0.82–1.43) | 1.11 (0.861–1.46) | 0.055 |
TG (mg/dL) | 149 (112–201) | 148 (109–203) | 145 (108–196) | 0.864 |
FGLUC (mg/dL) | 105 (95.4–119) | 102 (94–118) | 101 (92.7–118) | 0.162 |
HbA1c (%) | 6.31 (1.31) | 6.31 (1.23) | 6.31 (1.25) | 0.998 |
Systolic BP (mm Hg) | 142 (24.1) | 141 (23.9) | 141 (23.1) | 0.903 |
Diastolic BP (mm Hg) | 81.2 (11.8) | 80.9 (11.4) | 81.1 (11.3) | 0.787 |
eGFR (mL/min/1.73m2) | 80.8 (21.4) | 81.5 (19.8) | 82.2 (20.4) | 0.413 |
hsCRP (mg/L) | 2.71 (1.21–7) | 3.49 (1.35–8.83) | 3.54 (1.28–8.59) | 0.032 |
IL-6 (mg/L) | 2.86 (1.68–5.39) | 3.24 (1.8–6.47) | 3.29 (1.91–5.93) | 0.058 |
SAA (mg/L) | 4.4 (2.5–8.5) | 5.3 (2.82–13.4) | 5.2 (3–12.2) | 0.002 |
Fibrinogen (mg/dL) | 369 (316-438) | 374 (316-449) | 380 (325-453) | 0.065 |
Leucocytes (/nL) | 6.7 (5.7–8.1) | 6.75 (5.6–8.1) | 6.72 (5.7–8.2) | 0.638 |
NT-proBNP (pg/mL) | 323 (109–940) | 288 (109–870) | 307 (104–894) | 0.914 |
Haptoglobin (mg/dL) | 167 (141–198) | 159 (121–206) | 126 (89–174) | <0.001 |
GGT (U/L) | 17 (10–29) | 17 (10–29) | 17 (11–29) | 0.909 |
GPT (U/L) | 12 (9–19) | 13 (9–19) | 13 (9–19) | 0.764 |
α-tocopherol (µmol/L) | 31.7 (26.8–36.9) | 31.2 (26.7–37.6) | 31.6 (27.1–37.9) | 0.875 |
α-Tocopherol/cholesterol | 5.9 (5.18–6.74) | 5.93 (5.22–6.88) | 5.95 (5.24–6.85) | 0.808 |
γ-tocopherol (µmol/L) | 1.49 (1.12–2.04) | 1.47 (1.1–2.02) | 1.45 (1.08–2.02) | 0.535 |
γ-tocopherol/cholesterol | 0.278 (0.211–0.382) | 0.278 (0.214–0.372) | 0.276 (0.209–0.376) | 0.564 |
Coronary artery disease (%) | 74.6 | 78.9 | 78.1 | 0.148 |
Hypertension (%) | 70.8 | 73 | 72.6 | 0.641 |
Active smoking (%) | 21.6 | 23.6 | 23.4 | 0.653 |
Diabetes mellitus (%) | 38.3 | 40.3 | 40.5 | 0.679 |
*Analysis of variance for continuous variables (non-normally distributed variables were log-transformed before entering analysis) and χ2 test for categorical variables.
BMI, body mass index; eGFR, estimated glomerular filtration rate; FGLUC, fasting glucose; GGT, gamma-glutamyl transferase; GPT, glutamic-pyruvate transaminase; HDL, high-density lipoprotein; hsCRP, high-sensitive C reactive protein; IL, interleukin; LDL, low-density lipoprotein; NT-proBNP, N-terminal B-type natriuretic peptide; SAA, serum amyloid A; TG, triglycerides; Total-C, total cholesterol.