N (used for paired t-test) | Baseline | 24 months | Mean difference (24 months vs baseline) | Paired sample t-test | Repeated measures analysis (GLM) | |
Mean (SD) | Mean (SD) | Mean (SD) | P value | P value | ||
Fasting glucose (mmol/L) | 151 | 8.7 (2.1) | 8.8 (2.5) | 0.12 (2.53) | 0.575 | 0.126 |
Total cholesterol (mmol/L) | 136 | 4.6 (1.2) | 4.8 (1.2) | 0.20 (1.23) | 0.057 | 0.247 |
HDL (mmol/L) | 139 | 1.3 (0.4) | 1.4 (0.5) | 0.17 (0.53) | <0.001 | 0.169 |
LDL (mmol/L) | 155 | 2.6 (1.0) | 2.8 (1.1) | 0.18 (1.06) | 0.040 | 0.331 |
Total cholesterol/HDL ratio | 126 | 3.9 (1.2) | 3.7 (1.3) | −0.22 (1.24) | 0.044 | 0.156 |
Triglycerides (mmol/L) | 134 | 2.1 (1.2) | 1.7 (1.1) | −0.34 (1.02) | <0.001 | 0.004 |
Body weight (kg) | 179 | 94.1 (15.6) | 87.0 (14.7) | −7.01 (6.84) | <0.001 | <0.0001 |
BMI (kg/m2) | 179 | 31.4 (4.3) | 29.0 (4.0) | −2.36 (2.28) | <0.001 | <0.0001 |
Waist circumference (cm) | 111 | 110.4 (12.2) | 102.5 (11.1) | −7.87 (8.24) | <0.001 | <0.0001 |
Subjective health parameters | ||||||
Health (score 1–10) | 195 | 6.9 (1.3) | 7.3 (1.6) | 0.42 (1.49) | <0.001 | <0.0001 |
Quality of life (score 1–10) | 195 | 7.4 (1.2) | 7.6 (1.4) | 0.28 (1.33) | 0.004 | 0.001 |
Fatigue (CIS score 20–140) | 195 | 64.3 (23.4) | 54.8 (24.4) | −9.53 (20.72) | <0.001 | <0.0001 |
BMI, body mass index; CIS, Checklist Individual Strength; GLM, generalised linear models; HDL, high-density lipoproteins; LDL, low-density lipoproteins.