Null modelModel 11Model 12Model 13
βP valueβP valueβP valueβP value
Intercept5.4074<0.0015.172<0.0015.1949<0.0015.2556<0.001
Time0.2067<0.0010.2002<0.0010.086540.0983
Short duration between dinner and bedtime vs >2 hours0.012510.65130.0096570.72840.033630.2105
Short duration × time−0.006710.6863−0.010020.5462−0.010940.5071
Higher TG in 2012 vs normal0.07234<0.001
TG × time−0.007840.5272
Higher BP in 2012 vs normal
BP × time
Higher BMI in 2012 vs normal−0.1232<0.001
BMI × time−0.013610.2589
Men vs women
Sex × time
Smoking vs non-smoking0.066360.0213
Smoking × time0.0058690.7277
Alcohol consumption vs no alcohol consumption0.050710.0141
Alcohol consumption × time0.012830.2836
Regular exercise vs no exercise−0.06409<0.001
Regular exercise × time0.024140.0184
AIC3268.91661.11659.51618.9
BIC3279.61682.21680.61640
Residual variance0.08885<0.0010.04919<0.0010.04921<0.0010.04918<0.001
  • AIC, Akaike information criterion; BIC, Bayesian information criterion; BMI, body mass index; BP, blood pressure; TG, triglyceride.