	Null model		Model 11		Model 12		Model 13
	β	P value	β	P value	β	P value	β	P value
Intercept	5.4074	<0.001	5.172	<0.001	5.1949	<0.001	5.2556	<0.001
Time			0.2067	<0.001	0.2002	<0.001	0.08654	0.0983
Short duration between dinner and bedtime vs >2 hours			0.01251	0.6513	0.009657	0.7284	0.03363	0.2105
Short duration × time			−0.00671	0.6863	−0.01002	0.5462	−0.01094	0.5071
Higher TG in 2012 vs normal							0.07234	<0.001
TG × time							−0.00784	0.5272
Higher BP in 2012 vs normal
BP × time
Higher BMI in 2012 vs normal							−0.1232	<0.001
BMI × time							−0.01361	0.2589
Men vs women
Sex × time
Smoking vs non-smoking			0.06636	0.0213
Smoking × time			0.005869	0.7277
Alcohol consumption vs no alcohol consumption					0.05071	0.0141
Alcohol consumption × time					0.01283	0.2836
Regular exercise vs no exercise							−0.06409	<0.001
Regular exercise × time							0.02414	0.0184
AIC	3268.9		1661.1		1659.5		1618.9
BIC	3279.6		1682.2		1680.6		1640
Residual variance	0.08885	<0.001	0.04919	<0.001	0.04921	<0.001	0.04918	<0.001

AIC, Akaike information criterion; BIC, Bayesian information criterion; BMI, body mass index; BP, blood pressure; TG, triglyceride.