Dietary fiber, potassium, magnesium and calcium in relation to the risk of preeclampsia

J Reprod Med. 2005 May;50(5):332-44.

Abstract

Objective: To explore the relation between preeclampsia risk and maternal intake of dietary fiber, potassium, magnesium and calcium.

Study design: We conducted a case-control study of 172 preeclamptics and 339 normotensive controls. Maternal dietary intake was assessed using a food frequency questionnaire. Logistic regression procedures were used to estimate the association between each dietary factor and preeclampsia risk.

Results: Fiber intake was inversely associated with the risk of preeclampsia. When extreme quartiles of total fiber intake were compared, the odds ratio (OR) for preeclampsia was 0.46 (95% confidence interval [CI] 0.23-0.92). The multivariate OR for preeclampsia for women in the top quartile of potassium intake (> 4.1 g/d) versus the lowest quartile (< 2.4 g/d) was 0.49 (95% CI 0.24-0.99). There was some evidence ofa reduced risk of preeclampsia with a high intake of magnesium and calcium, though these results were not statistically significant. Intake offruits and vegetables, low-fat dairy products, total cereal and dark bread were each associated with a reduced risk of preeclampsia.

Conclusion: Our results support previous reports that suggest that diets high in fiber and potassium are associated with a reduced risk of hypertension. Maternal intake of recommended amounts of foods rich in fiber, potassium and other nutrients may reduce the risk of preeclampsia.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Calcium, Dietary*
  • Case-Control Studies
  • Diet
  • Dietary Fiber*
  • Female
  • Humans
  • Magnesium / administration & dosage*
  • Potassium / administration & dosage*
  • Pre-Eclampsia / etiology*
  • Pre-Eclampsia / prevention & control
  • Pregnancy
  • Risk Factors

Substances

  • Calcium, Dietary
  • Dietary Fiber
  • Magnesium
  • Potassium