[HTML][HTML] Meta-analysis of sub-Saharan African studies provides insights into genetic architecture of lipid traits
Genetic associations for lipid traits have identified hundreds of variants with clear differences
across European, Asian and African studies. Based on a sub-Saharan-African GWAS for …
across European, Asian and African studies. Based on a sub-Saharan-African GWAS for …
[HTML][HTML] Genetic associations with carotid intima-media thickness link to atherosclerosis with sex-specific effects in sub-Saharan Africans
Atherosclerosis precedes the onset of clinical manifestations of cardiovascular diseases
(CVDs). We used carotid intima-media thickness (cIMT) to investigate genetic susceptibility …
(CVDs). We used carotid intima-media thickness (cIMT) to investigate genetic susceptibility …
[HTML][HTML] Apolipoprotein L1 high-risk genotypes and albuminuria in sub-Saharan African populations
JT Brandenburg, MA Govender… - Clinical Journal of the …, 2022 - journals.lww.com
Results High G1 allele frequencies occurred in South and West Africa (approximately 7%–
13%). G2 allele frequencies were highest in South Africa (15%–24%), followed by West …
13%). G2 allele frequencies were highest in South Africa (15%–24%), followed by West …
[HTML][HTML] Prevalence and socio-demographic correlates of tobacco and alcohol use in four sub-Saharan African countries: a cross-sectional study of middle-aged …
Background Substance misuse is a global public health problem. In addition to social and
economic concerns, consumption of tobacco and alcohol is associated with susceptibility to …
economic concerns, consumption of tobacco and alcohol is associated with susceptibility to …
[HTML][HTML] The changing epidemiology of hepatitis B and C infections in Nanoro, rural Burkina Faso: a random sampling survey
M Lingani, T Akita, S Ouoba, S Nagashima… - BMC Infectious …, 2020 - Springer
Background This study sought to provide up-to-date hepatitis B (HBV) and C (HCV)
seroprevalence in rural Burkina Faso decade after hepatitis B vaccine was introduced in the …
seroprevalence in rural Burkina Faso decade after hepatitis B vaccine was introduced in the …
[HTML][HTML] Novel and known gene-smoking interactions with cIMT identified as potential drivers for atherosclerosis risk in West-African populations of the AWI-Gen study
Introduction Atherosclerosis is a key contributor to the burden of cardiovascular diseases
(CVDs) and many epidemiological studies have reported on the effect of smoking on carotid …
(CVDs) and many epidemiological studies have reported on the effect of smoking on carotid …
Undernutrition in children aged 0–59 months by region and over time: secondary analysis of the Burkina Faso 2012–2018 National Nutrition Surveys
The global burden of undernutrition remains high, responsible for significant under-five
mortality in resource-limited settings. Numerous sustainable development goals (SDGs) are …
mortality in resource-limited settings. Numerous sustainable development goals (SDGs) are …
Genetically predicted lipid traits, diabetes liability, and carotid intima-media thickness in African ancestry individuals: a mendelian randomization study
Carotid intima-media thickness (cIMT) is a measure of atherosclerosis used to predict
cardiovascular disease. 1 Lipid traits and type 2 diabetes (T2D) have been implicated in the …
cardiovascular disease. 1 Lipid traits and type 2 diabetes (T2D) have been implicated in the …
Genetic Association and Transferability for Urinary Albumin-Creatinine Ratio as a Marker of Kidney Disease in four Sub-Saharan African Populations and non …
JT Brandenburg, WC Chen, PR Boua, MA Govender… - medRxiv, 2024 - medrxiv.org
Background Genome-wide association studies (GWAS) have predominantly focused on
populations of European and Asian ancestry, limiting our understanding of genetic factors …
populations of European and Asian ancestry, limiting our understanding of genetic factors …
[HTML][HTML] Genetic insights into smoking behaviours in 10,558 men of African ancestry from continental Africa and the UK
Smoking is a leading risk factor for many of the top ten causes of death worldwide. Of the 1.3
billion smokers globally, 80% live in low-and middle-income countries, where the number of …
billion smokers globally, 80% live in low-and middle-income countries, where the number of …