[HTML][HTML] Declining bowel cancer incidence and mortality in Germany: an analysis of time trends in the first ten years after the introduction of screening colonoscopy

H Brenner, P Schrotz-King, B Holleczek… - Deutsches Ärzteblatt …, 2016 - ncbi.nlm.nih.gov
Background In October 2002, screening colonoscopy from age 55 onward was introduced
as part of the German national statutory cancer screening program. Screening colonoscopy …

Potential of fecal microbiota for early‐stage detection of colorectal cancer

G Zeller, J Tap, AY Voigt, S Sunagawa… - Molecular systems …, 2014 - embopress.org
Several bacterial species have been implicated in the development of colorectal carcinoma
(CRC), but CRC‐associated changes of fecal microbiota and their potential for cancer …

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

J Wirbel, PT Pyl, E Kartal, K Zych, A Kashani… - Nature medicine, 2019 - nature.com
Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …

Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation

AM Thomas, P Manghi, F Asnicar, E Pasolli… - Nature medicine, 2019 - nature.com
Several studies have investigated links between the gut microbiome and colorectal cancer
(CRC), but questions remain about the replicability of biomarkers across cohorts and …

[HTML][HTML] Metabolomics biomarkers for detection of colorectal neoplasms: a systematic review

V Erben, M Bhardwaj, P Schrotz-King, H Brenner - Cancers, 2018 - mdpi.com
Background: Several approaches have been suggested to be useful in the early detection of
colorectal neoplasms. Since metabolites are closely related to the phenotype and are …

Effects of vitamin D supplementation on inflammatory response in patients with cancer and precancerous lesions: Systematic review and meta-analysis of randomized …

T Gwenzi, A Zhu, P Schrotz-King, B Schöttker… - Clinical Nutrition, 2023 - Elsevier
Background and aims Inflammation plays a key role in tumor development and progression.
Vitamin D has potential tumor suppressing effects through modulation of inflammatory …

Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations

L Huang, L Jansen, Y Balavarca, E Molina-Montes… - Gut, 2019 - gut.bmj.com
Objective Resection can potentially cure resectable pancreatic cancer (PaC) and
significantly prolong survival in some patients. This large-scale international study aimed to …

[HTML][HTML] Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare …

DB Liesenfeld, D Grapov, JF Fahrmann, M Salou… - The American journal of …, 2015 - Elsevier
Background: Metabolic and transcriptomic differences between visceral adipose tissue
(VAT) and subcutaneous adipose tissue (SAT) compartments, particularly in the context of …

[HTML][HTML] Stratified survival of resected and overall pancreatic cancer patients in Europe and the USA in the early twenty-first century: a large, international population …

L Huang, L Jansen, Y Balavarca, M Babaei… - BMC medicine, 2018 - Springer
Background The prognosis of pancreatic cancer (PaC) strongly varies across different
stages and age groups, which has unfortunately not been well recorded in the literature …

[HTML][HTML] Direct comparison of diagnostic performance of 9 quantitative fecal immunochemical tests for colorectal cancer screening

A Gies, K Cuk, P Schrotz-King, H Brenner - Gastroenterology, 2018 - Elsevier
Background & Aims A variety of fecal immunochemical tests (FITs) for hemoglobin (Hb) are
used in colorectal cancer screening. It is unclear to what extent differences in reported …