Necrotizing enterocolitis (NEC) presents as the most common gastrointestinal emergency
during the neonatal period and results in ulceration and necrosis of the distal small intestine …

Pdcd4 is a novel transformation suppressor that is highly expressed in promotion-resistant
(P−) mouse epidermal JB6 cells but not in susceptible (P+) cells. Overexpression of pdcd4 …

PURPOSE: Infants with multiple cutaneous hemangiomas often present with hepatic
hemangiomas. They can follow a benign clinical course or require complex management …

Mitogen-activated protein (MAP) kinase, extracellular-signal-regulated kinases (ERKs) play
an important role in activating AP-1-dependent transcription. Studies using the JB6 mouse …

The function of retinoblastoma protein (pRb) in the regulation of small intestine epithelial cell
homeostasis has been challenged by several groups using various promoter-based Cre …

PURPOSE: Adaptive growth of the intestinal mucosa in response to massive gut loss is
fundamental for autonomy from parenteral nutrition. Although angiogenesis is essential for …

BACKGROUND: Pancreatic fistula (PF) formation is a known complication of pancreatic
surgery, pancreatitis, and pancreatic injury. When medical or endoscopic interventions fail to …

BACKGROUND: Intestinal adaptation after massive small bowel resection (SBR) involves all
layers of the bowel wall. Most prior work has focused on changes that occur in the intestinal …

PURPOSE: Central to the use of murine models of disease is the ability to derive
reproducible data. The purpose of this study was to determine factors contributing to …

Background Malnutrition in children is widely prevalent around the world. It has been
observed that malnourished children with multiple anthropometric deficits have higher …