Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies
…, M Fiander, DS MacKay, J McGavock, B Wicklow… - Cmaj, 2017 - Can Med Assoc
BACKGROUND Nonnutritive sweeteners, such as aspartame, sucralose and stevioside, are
widely consumed, yet their long-term health impact is uncertain. We synthesized evidence …
widely consumed, yet their long-term health impact is uncertain. We synthesized evidence …
ISPAD Clinical Practice Consensus Guidelines 2022: Type 2 diabetes in children and adolescents
…, PS Zeitler, J Wong, AS Pena, B Wicklow… - Pediatric …, 2022 - Wiley Online Library
Since the 2018 ISPAD guidelines on this topic, follow‐up of large cohorts from around the
globe have continued informing the current incidence and prevalence of co‐morbidities and …
globe have continued informing the current incidence and prevalence of co‐morbidities and …
Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring
…, SM Kereliuk, CA Doucette, BA Wicklow… - Critical reviews in …, 2018 - Taylor & Francis
Since 1980, global obesity has doubled, and the incidence of cardiometabolic diseases such
as type 2 diabetes and heart disease is also increasing. While genetic susceptibility and …
as type 2 diabetes and heart disease is also increasing. While genetic susceptibility and …
Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder …
…, TJ Salo, H Zhang, BA Wicklow… - Proceedings of the …, 1999 - National Acad Sciences
Hyaluronan (HA), a large glycosaminoglycan abundant in the extracellular matrix, is important
in cell migration during embryonic development, cellular proliferation, and differentiation …
in cell migration during embryonic development, cellular proliferation, and differentiation …
Efficacy and safety of the SGLT2 inhibitor empagliflozin versus placebo and the DPP-4 inhibitor linagliptin versus placebo in young people with type 2 diabetes …
…, RS Weinstock, MD Wheeler, BA Wicklow… - The lancet Diabetes & …, 2023 - thelancet.com
Background The incidence of type 2 diabetes in young people is increasing, but treatments
remain limited. We aimed to assess the efficacy and safety of an empagliflozin dosing …
remain limited. We aimed to assess the efficacy and safety of an empagliflozin dosing …
Sex differences in kidney metabolism may reflect sex-dependent outcomes in human diabetic kidney disease
…, A Köttgen, AB Dart, B Wicklow… - Science translational …, 2024 - science.org
Diabetic kidney disease (DKD) is the main cause of chronic kidney disease (CKD) and
progresses faster in males than in females. We identify sex-based differences in kidney …
progresses faster in males than in females. We identify sex-based differences in kidney …
[HTML][HTML] Dietary determinants of hepatic steatosis and visceral adiposity in overweight and obese youth at risk of type 2 diabetes
…, M Senechal, AC MacIntosh, J Hay, BA Wicklow… - The American journal of …, 2014 - Elsevier
Background: Dietary determinants of hepatic steatosis, an important precursor for nonalcoholic
fatty liver disease, are undefined. Objective: We explored the roles of sugar and fat intake …
fatty liver disease, are undefined. Objective: We explored the roles of sugar and fat intake …
Early exposure to nonnutritive sweeteners and long-term metabolic health: a systematic review
…, M Fiander, DS MacKay, J McGavock, B Wicklow… - …, 2016 - publications.aap.org
OBJECTIVE: To synthesize evidence from prospective studies evaluating the association of
early-life NNS exposure and long-term metabolic health. DATA SOURCES: Medline, Embase…
early-life NNS exposure and long-term metabolic health. DATA SOURCES: Medline, Embase…
Association of gestational diabetes and type 2 diabetes exposure in utero with the development of type 2 diabetes in First Nations and non–First Nations offspring
BA Wicklow, EAC Sellers, AK Sharma, K Kroeker… - JAMA …, 2018 - jamanetwork.com
Importance Type 2 diabetes is increasing worldwide, disproportionately affecting First Nations
(FN) people. Identifying early-life determinants of type 2 diabetes is important to address …
(FN) people. Identifying early-life determinants of type 2 diabetes is important to address …
Cardiorespiratory fitness and adiposity in metabolically healthy overweight and obese youth
M Sénéchal, B Wicklow, K Wittmeier, J Hay… - …, 2013 - publications.aap.org
OBJECTIVE: Controversy exists surrounding the contribution of fitness and adiposity as
determinants of the Metabolically Healthy Overweight (MHO) phenotype in youth. This study …
determinants of the Metabolically Healthy Overweight (MHO) phenotype in youth. This study …