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Abstract
Introduction A key Sustainable Development Goal target is to eliminate all forms of malnutrition. Existing evidence suggests children with disabilities are at greater risks of malnutrition, exclusion from nutrition programmes and mortality from severe acute malnutrition than children without disabilities. However, there is limited evidence on the nutritional outcomes of children with disabilities in large-scale global health surveys.
Methods We analysed Multiple Indicator Cluster Survey data from 30 low and middle-income countries to compare nutritional outcomes for children aged 2–4 years with and without disabilities. We estimated the adjusted prevalence ratios for stunting, wasting and underweight comparing children with and without disabilities by country and sex, using quasi-Poisson models with robust SEs. We accounted for the complex survey design, wealth quintile, location and age in the analyses. We meta-analysed these results to create an overall estimate for each of these outcomes.
Results Our analyses included 229 621 children aged 2–4 across 30 countries, including 15 071 children with disabilities (6.6%). Overall, children with disabilities were more likely to be stunted (adjusted risk ratio (aRR) 1.16, 95% CI 1.11 to 1.20), wasted (aRR 1.28, 95% CI 1.18 to 1.39) and underweight (aRR 1.33, 95% CI 1.17, 1.51) than children without disabilities. These patterns were observed in both girls and boys with disabilities, compared with those without.
Conclusion Children with disabilities are significantly more likely to experience all forms of malnutrition, making it critical to accelerate efforts to improve disability inclusion within nutrition programmes. Ending all forms of malnutrition will not be achievable without a focus on disability.
- Malnutrition
Data availability statement
Data are available in a public, open access repository. All data are available on the MICS website and are free to download.
This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
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WHAT IS ALREADY KNOWN ON THIS TOPIC
Prior research has shown children with disabilities in low and middle-income countries have higher prevalence of stunting, wasting and underweight and worse outcomes and mortality from severe acute malnutrition.
WHAT THIS STUDY ADDS
We show that children with disabilities, overall and by sex, have significantly higher rates of stunting, wasting and underweight than children without disabilities.
This study adds to the existing evidence on disability-based inequities in nutritional outcomes from nationally representative, internationally comparable household surveys in multiple countries.
HOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICY
A twin-track approach is needed to ensure children with disabilities are reached in mainstream nutrition programmes, as well as having their specific and additional needs met through targeted programmes.
Without sufficient focus on disability, it will be impossible to achieve Sustainable Development Goal 2, to end all forms of child nutrition or meet global child mortality reduction targets.
Introduction
Malnutrition is a major contributor to child mortality worldwide.1 It often arises from a complex interaction of factors, including socioeconomic status, gender inequality, political instability, food insecurity and poor nutritional intake.2 However, access to and experiences of adequate nutrition vary among children, and challenges with these can hinder their development and compromise their well-being. Certain groups, such as children with disabilities, may be at particular risk of inadequate nutrition. Prior research has shown that children with disabilities have higher prevalence of malnutrition and its sequelae. This is a consequential relationship for the nearly 240 million children with disabilities worldwide.3 For example, a 2017 systematic review found that children with disabilities had nearly three times higher odds of being underweight (OR 2.97, 95% CI 2.33 to 3.79) and two times higher odds of being stunted or wasted (stunting: OR 1.82, 95% CI 1.40 to 2.36; wasting: OR 1.90, 95% CI 1.32 to 2.75) compared with children without disabilities.4 However, these studies used variable definitions of disability and malnutrition, making international comparison difficult. A longitudinal cohort study in Malawi showed that children with disabilities also have significantly higher mortality rates from severe acute malnutrition than children without disabilities (mortality HR 2.29, 95% CI 1.51 to 3.45).5 Further, while some types of impairments may make the use of standardised measures of nutritional status invalid (eg, growth restriction or limb difference),6 these conditions do not occur at sufficiently high prevalence to distort estimates drawn from large samples. Indeed, previous descriptive analysis of the Multiple Indicator Cluster Survey (MICS) has shown that children with functional difficulty in the walking, playing and fine motor domains have the highest prevalence of stunting, wasting and underweight.3
It is well established that the relationship between impairment and malnutrition is likely to be bidirectional,7 with children with disabilities more at risk of malnutrition4 and children with severe acute malnutrition more at risk of acquiring impairments.8 9 Some proportion of the difference may be linked to a child’s impairment. For example, there is evidence that functional limitations, feeding difficulties and inadequate energy intake are key risk factors that lead children with cerebral palsy to be malnourished.10 While nutritional disorders are common among some impairment types (such as cerebral palsy),10–13 these inequities are inexplicable by impairment alone. Moreover, several of the social factors that lead to worse nutritional outcomes are also more prevalent in children with disabilities. For example, inequities in maternal education, poverty, parental employment status, and access to water, sanitation and hygiene (WASH) and information and communication technology are closely linked to inequities in both nutritional status14 and disability.15–18 Similarly, recent research has highlighted that children with disabilities have higher occurrence of common childhood illnesses, such as acute respiratory infection, fever and diarrhoeal disease,19 20 which are known to co-occur with wasting and other equity-related variables.21
Despite the evidence for this bidirectional relationship, as well as the overlap between regions with high malnutrition prevalence22 and those with high childhood disability prevalence,23 disability is not sufficiently attended to in guidelines on malnutrition, putting children with disabilities at greater risk of adverse outcomes from malnutrition and other nutritional disorders.24 Since tackling all forms of malnutrition is one of the targets of Sustainable Development Goal 2 (SDG 2), it is also important to understand how children with disabilities are being reached in these efforts.25 Without a focus on disability, there is the risk of leaving these children behind.26 This is likely to require a twin-track approach, which involves simultaneously addressing the specific needs and challenges faced by a particular group, such as children with disabilities, while also implementing broader strategies to achieve a larger goal, such as improving nutritional status and addressing malnutrition for all children. However, more evidence is needed on the association between disability and nutritional status.
The MICS provides an opportunity to fill the evidence gap by drawing on internationally comparable data with comparable measures of disability and malnutrition. While a recent UNICEF report presented some descriptive analysis for all countries combined and by impairment,3 this analysis will look at relative and absolute inequities across gender and disability. The aim of this paper is therefore to use MICS data to examine relative inequities in malnutrition indicators by disability status and sets out to answer the question: are children with disabilities more likely to be stunted, wasted or underweight than children without disabilities?
Methods
Data source
We used data from the sixth round of the UNICEF-supported MICS conducted between 2017 and 2021 in 30 countries. All data were publicly available on the MICS data repository as of April 2023. The MICS uses a multistage probability sampling methodology to generate nationally representative data on indicators for monitoring progress towards the SDGs, health and human development.27 The current analyses focus on MICS data from 30 countries where information was available on both disability status and nutrition among children aged 2–4. Trained interviewers conducted household-based surveys with randomly selected households. All children aged 2–4 within selected households were eligible to participate.27 The survey questions were standardised across countries to enable comparative analyses. We included data from all publicly available MICS surveys as of April 202328 that contained information on the variables of interest.
Exposure
Disability was measured using the Washington Group/UNICEF child functioning module (CFM) for children aged 2–4 years. The CFM set is included in MICS6 surveys and offers a comparable definition of disability across countries. The tool has been validated across countries and is used to provide a standardised measurement and definition that remains valid across each MICS setting.29 Caregivers were asked about their child’s functioning across the eight identified functional domains: vision, hearing, communication, walking, controlling behaviour, learning, fine motor skills and playing. Children were considered disabled if their caregiver reported ‘a lot of difficulty’ or ‘cannot do at all’ in at least one functional domain.
Outcomes
Data available for download on the MICS data are cleaned to provide a z-score for children’s weight for age (underweight), weight for height (wasting) and height for age (stunting) compared with the WHO Child Growth Standards. Children whose standardised z-scores are 2 or more SDs from the WHO Child Growth Standards are recoded as underweight, wasted or stunted.30
Covariates
Age was reported by caregivers, while location was determined according to the area in which participants were selected for the survey. Wealth status was calculated by UNICEF according to data on household characteristics, household and personal assets and WASH via principal components analysis.31
Statistical analysis
All analyses were conducted using R statistical software V.4.2.2 (R Core Team, 2022) and statistical significance was determined as p<0.05. Outcomes, exposures and covariates were described by country and sex using summary statistics. Continuous data were reported as mean (SD) and categorical data as frequencies (percentage).
To estimate the relative inequality in each outcome between children with and without disabilities, modified Poisson regression models were fitted to estimate the risk ratio (RR)32 and 95% CI for each outcome by country and by country and sex, adjusting for age, residence place and wealth status. The complex survey design and sample weights were accounted for using the ‘survey’ package in R.33 Country-specific RRs were pooled via random-effects meta-analysis if significant heterogeneity was detected across countries per Cochran’s Q test (p<0.1), otherwise fixed-effects meta-analysis was used.
Records with missing data were excluded from analyses rather than imputed. To minimise bias from small sample sizes, countries with fewer than 25 respondents with disabilities were excluded when pooling estimates.
Results
220 621 children aged 2–4 were eligible for inclusion across 30 countries (table 1). Country sample sizes ranged from 1268 children in Kiribati to 67 612 children in Pakistan (including only Balochistan, Khyber Pakhtunkhwa, Sindh and Punjab provinces). The sample includes 15 071 children with disabilities (6.6%) overall, though country prevalence ranged from 2.0% (n=68) in Cuba to 14.4% (n=784) in Central African Republic. The sample had a mean age of 3.01 years (SD: 0.81) and was 51% male (n=117 132). Most of the sample lived in rural areas (67.6%, n=155 120). In the overall sample, 31.6% of children were stunted (n=72 489), 5.9% were wasted (n=13 606) and 18.6% were underweight (n=42 716).
Baseline characteristics of the sample
Underweight
Across all countries, children with disabilities were more likely to be underweight compared with children without disabilities (table 2: adjusted RR (aRR) 1.33, 95% CI 1.17 to 1.51; online supplemental figure 1). While many samples had small numbers and wide CIs, there was evidence children with disabilities were significantly more likely to be underweight in 13 countries. However, in Ghana (aRR 0.65, 95% CI 0.45 to 0.95) and Suriname (aRR 0.12, 95% CI 0.02 to 0.88), children with disabilities were less likely to be underweight than children without disabilities.
Supplemental material
Unadjusted and adjusted risk ratios for stunting, wasting and underweight for children with disabilities compared with children without disabilities
In terms of sex differences, both girls (aRR 1.40, 95% CI 1.20 to 1.63; online supplemental figure 2) and boys (aRR 1.30, 95% CI 1.18 to 1.43; online supplemental figure 3) with disabilities were significantly more likely to be underweight than girls and boys without disabilities, respectively. For girls, there was significant evidence from nine countries that girls with disabilities were more likely to be underweight than girls without disabilities, while there was no evidence that girls with disabilities were less to be underweight than girls without disabilities in any country. Boys were also more likely to be underweight in 11 countries, though there was evidence from Ghana that boys with disabilities were less likely to be underweight than boys without disabilities (aRR 0.55, 95% CI 0.32 to 0.95).
Wasted
Children with disabilities were significantly more likely to be wasted than children without disabilities (aRR 1.28, 95% CI 1.18 to 1.39; online supplemental figure 4) across all countries. Children with disabilities were at greater risk of being wasted in eight countries, although the small number of children with disabilities with wasting resulted in wide CIs for all countries. There was no evidence to suggest that children with disabilities were less likely to be wasted than children without disabilities in any country.
Girls with disabilities were significantly more likely to be wasted than girls without disabilities (aRR 1.47, 95% CI 1.32 to 1.63; online supplemental figure 5) globally. Most countries showed no differences between girls with and without disabilities, except for Chad, Madagascar, Malawi, Mongolia, Pakistan and State of Palestine, where significantly higher rates of wasting were observed. Among boys, those with disabilities had significantly higher likelihood of being wasted than those without (aRR 1.28, 95% CI 1.04 to 1.58; online supplemental figure 6). In four countries, boys with disabilities were significantly more likely to be wasted than boys without disabilities, while none of the countries indicated evidence that boys with disabilities were less likely to be wasted than boys without disabilities.
Stunted
Children with disabilities were significantly more likely to be stunted than children without disabilities (aRR 1.16, 95% CI 1.11 to 1.20; online supplemental figure 7). In 14 countries, children with disabilities had a higher likelihood of stunting, while no countries showed evidence of children with disabilities being less likely to be stunted. Both girls and boys with disabilities had significantly higher rates of stunting compared with their counterparts without disabilities (girls: aRR 1.20, 95% CI 1.12 to 1.28; online supplemental figure 8; boys: prevalence aRR 1.14, 95% CI 1.10 to 1.17; online supplemental figure 9). For each sex, there was no evidence the children with disabilities had lower prevalence of stunting than children without disabilities. However, most countries had small sample sizes and wide CIs.
Discussion
Using comparable data from 30 countries, we found that young children with disabilities are significantly more likely to be stunted, wasted and underweight than children without disabilities. In sex-disaggregated analyses, both boys and girls are also significantly more likely to be malnourished than boys and girls without disabilities, respectively. The findings presented here have profound implications for meeting the lifelong impacts of malnutrition in childhood, as programmes will need to work to address the disproportionate prevalence of malnutrition on children with disabilities. These findings also highlight that achieving SDG 2 and global child mortality reduction targets will be impossible without a sufficient focus on disability inclusion.
Our study adds to the body of evidence that has shown higher prevalence and adverse impacts of nutritional disorders in young children with disabilities compared with those without disabilities.4 A 2017 systematic review of 17 studies found that children with disabilities in low and middle-income countries (LMICs) were nearly three times more likely to be underweight and nearly two times more likely to be wasted or stunted compared with children without disabilities.4 Other studies have also produced evidence for specific impairments and/or geographic locations. For example, a systematic review of malnutrition among children and adolescents with cerebral palsy in Arab-speaking countries found that children with cerebral palsy had substantially higher prevalence of malnutrition.10 Prior evidence from Malawi has also showed that children with disabilities were more likely to have adverse outcomes from severe acute malnutrition than children without disabilities.5
Our findings have a range of policy and programmatic implications. First, while there has been increasing focus on addressing various social inequities in malnutrition programmes, these have been insufficient with regard to disability.24 Various barriers exist for caregivers of children with disabilities to access health and nutritional services,20 34 as these data provide further evidence that urgent action is needed to close these gaps. A health systems approach can play a crucial role in addressing these differences for children with disabilities. For example, given the lack of disability-specific guidelines on nutrition programming and invisibility in mainstream nutrition programmes,24 governments, international organisations, donors and non-governmental organisations alike can improve how children with disabilities are included in nutrition policies, guidelines and programmes. In terms of health financing, it is essential key stakeholders develop specific programmes and budget lines to target children with disabilities. Identifying children with disabilities within the primary care system and referring those at risk of malnutrition to care would strengthen coordination between primary care and more specialised services and rehabilitation. Nurses, midwives, skilled birth attendants and community health workers need to receive training to recognise children with disabilities and nutritional deficiencies, offer precise parental education regarding disabilities, which can help diminish stigma, misinformation35 and potential risks of abuse or neglect for the child, and appropriately refer these children to the required services. Given the higher prevalence of malnutrition outcomes for girls, there is also evidence to suggest a gender-sensitive approach is needed.34
Additionally, stakeholders can cocreate curricula and programmes for parents of children with disabilities to address some of the stigma and cultural attitudes surrounding feeding and health practices for children with disabilities.34 By building awareness and providing financial support and incentives to improve nutrition, parents of children with disabilities can be supported to improve awareness, feeding practices and outcomes. Prior research has shown that these interventions may be promising to support these parents, and so further expansion of this may be beneficial.36 Furthermore, more training for health workers is needed to support identification of children with disabilities, tackle stigma towards children with disabilities,37 as well as those at risk of malnutrition. Upskilling health workers on disability awareness, addressing stigma and improving knowledge on malnutrition will help provide earlier intervention and greater support to children with disabilities experiencing malnutrition. However, recent mapping to understand key research gaps for children with disabilities suggests more research is needed to understand the interventions that can help close these inequities for disabled children.38
It is crucial for future nutrition policy and programming, maternal and child health, and disability policy to acknowledge and address the connection between malnutrition and disability. This work should be twin tracked to ensure children with disabilities are reached in mainstream efforts, but also ensure that the specific needs of children with disabilities are included. For example, children with disabilities may need to have tailored programmes because of additional and specific feeding difficulties (ie, children with autism may have difficulty tolerating different food textures)39 40 and because of the specific exclusions this population faces (ie, exclusion from education means excluded children with disabilities are not included in school-based nutrition programmes).41 By doing so, existing challenges can be transformed into opportunities to benefit both areas of healthcare, requiring adequate resources and effective action planning. Including children with disabilities in nutrition services and considering their specific needs will contribute to inclusive and equitable access to nutrition as a fundamental human right.7
Finally, all malnutrition programmes should collect disability data to understand how they are reaching children with disabilities, as well as the outcomes for this population. This is particularly important to examine through the lens of different impairments to see if further targeted interventions are required. Through this system-level approach, it will be possible to ensure that these inequities for children with disabilities are addressed in the global efforts to end all forms of malnutrition by 2030.
Strengths and limitations
This is the largest study to date to examine disability and sex-based inequities in key malnutrition outcomes for nearly 230 000 children in household surveys across 30 LMICs. The large-scale, high-quality and internationally comparable UNICEF-supported MICS data provide strong evidence for these inequities and should be used as motivation to address these inequities. However, this analysis also has several limitations. First, the small numbers of children with certain outcomes means that much of the sex-disaggregated data had small numbers and wide CIs, limiting our ability to draw conclusions about the intersectional barriers children with disabilities may experience. Second, the overlap of the Washington Group Questions and the outcome of interest hampers our ability to look at younger children or other important covariates (ie, breast feeding) that may impact nutrition outcomes. Finally, the MICS anthropomorphic measurement manual does not mention disability, meaning the growth standards and measurements may not capture all children with disabilities (ie, a child with short stature is not captured as stunted because it does not use expected height, rather than actual height). Therefore, these results likely underestimate the burden of nutritional disorders among children with disabilities.
Conclusion
Children with disabilities are unacceptably over-represented in all three key malnutrition indicators—stunting, wasting and underweight. These relative inequities are not due to impairment alone and need to be urgently addressed in order to reach the SDG targets. Concerted efforts to improve disability in nutrition programmes and throughout the health system are urgently needed. Without a focus on disability, we risk perpetuating inequities in malnutrition and related mortality—an unacceptable violation of the human right to health of children with disabilities.
Data availability statement
Data are available in a public, open access repository. All data are available on the MICS website and are free to download.
Ethics statements
Patient consent for publication
Ethics approval
This study involves human participants and was approved by the London School of Hygiene & Tropical Medicine Research Ethics Committee on 9 November 2020 (ref: 22719). Participants agreed to be part of the MICS survey and have their anonymised data publicly available on the MICS website. We accessed only publicly available data from the MICS website for these analyses.
References
Supplementary materials
Supplementary Data
This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.
Footnotes
Twitter @SaraRotenberg
Contributors SR conceived the study, recoded the data, wrote the first draft of the manuscript, and is the guarantor of the study. SC conducted the analysis. SC, XH, TS and HK reviewed the draft and provided meaningful contributions to the manuscript.
Funding Funding from this study came from the Programme for Evidence to Inform Disability Action (PENDA) funded by FCDO. SR received funding from the Rhodes Trust and TS and HK are funded by an NIHR Global Professorship.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.